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背景与目的光动力学疗法(PDT)是对化疗和放疗已产生耐药的肿瘤的一种替代疗法。该方法主要通过激光照射光敏剂产生活性氧,继而杀死肿瘤细胞。有研究表明抑癌蛋白P53能使人类某些肿瘤细胞对PDT治疗更加敏感。但是,目前仍然没有直接的证据来证明这一观点。本研究旨在探讨肿瘤细胞
Background and Objective Photodynamic therapy (PDT) is an alternative to chemotherapy-and radiation-resistant tumors. The method mainly generates active oxygen by irradiating a photosensitizer with a laser and then kills the tumor cells. Studies have shown that the tumor suppressor protein P53 can make certain human tumor cells more sensitive to PDT treatment. However, there is still no direct evidence to support this view. This study aimed to explore tumor cells