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组织学研究表明，黄瓜霜霉菌在不同抗病类型品种上，其侵入前的过程基本相似，并且都能形成胞间菌丝和吸器。然而，随着品种抗病性的增强，吸器形成速率变慢，数目减少，同时菌丝扩展缓慢；寄主细胞坏死发生时间早，机率高。电镜观察显示，抗病品种中菌丝和吸器的细胞质中液泡数量增加，菌丝和吸器的壁与细胞质膜分离，原生质电子致密度加深，最后菌丝和吸器解体；受侵寄主细胞分泌的胼胝质，可将吸器体完全包围，从而阻止了吸器的进一步发育；在发生坏死的寄主细胞中，吸器也解体坏死。
Histological studies show that the cucumber downy mildew in different types of disease resistance, the process of their invasion is basically similar, and can form interstitial hyphae and inhalers. However, with the enhancement of disease resistance, the formation rate of aspirate decreased, the number decreased, and mycelium expanded slowly. The host cell necrosis occurred earlier and had a higher probability. Electron microscopy showed that the number of vacuoles increased in the cytoplasm of mycelium and aspirator in resistant varieties, the walls of mycelium and aspirator were separated from the cytoplasmic membrane, the proton electron density was deepened, and finally the mycelium and the aspirate were disintegrated. The calluses secreted by the host cells Quality, can completely surround the body of the inhaler, thus preventing the further development of the inhaler; In the necrotic host cells, the inhaler also disintegrates necrosis.