The problem of differentiated Multi-Layer Integrated Survivability (MLIS) in IP over WDM networks is studied, which is decomposed into three sub-problems: survivable strategies design (SSD), spare capacity dimensioning (SCD), and dynamic survivable routing (DSR). A related work of network survivability in IP over WDM networks is firstly provided, and adaptive survivable strategies are also designed. A new Integrated Shared Pool (ISP) approach for SCD is then proposed, which is formulated by using integer-programming theory. Moreover, a novel survivable routing scheme called Differentiated Integrated Survivability Algorithm (DISA) for DSR is developed. Simulation results show that the proposed integrated survivability scheme performs much better than other solutions (e.g., "highest layer recovery" and "lowest layer recovery" schemes) in terms of traffic blocking ratio, spare resource requirement, and average traffic recovery ratio in IP over WDM networks.