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为观察应用胰岛素泵治疗儿童及青少年1型糖尿病(T1DM)对糖代谢的影响 ,随访10例胰岛素泵治疗的T1DM患儿 ,分别观察胰岛素泵治疗前、后6个月的糖化血红蛋白值(HbA1c)、胰岛素用量、严重低血糖及酮症酸中毒发生次数的变化情况。结果显示 ,胰岛素泵治疗6个月后HbA1c 显著下降 ,治疗前为8.97 %±1.69 %,治疗后为7.51 %±1.17 % (t=2.52 ,P<0.05) ;胰岛素用量无显著下降 ;未发生严重低血糖和酮症酸中毒。表明胰岛素泵治疗可有效控制血糖 ,明显降低HbA1c,减少低血糖及酮症酸中毒的发生 ,是儿童及青少年T1DM常规治疗的较好选择。
To observe the effect of insulin pump on glucose metabolism in children and adolescent with type 1 diabetes (T1DM), 10 cases of T1DM treated with insulin pump were followed up for 6 months before and after insulin pump to observe the changes of HbA1c, , The amount of insulin, severe hypoglycemia and ketoacidosis changes in the frequency of occurrence. The results showed that HbA1c decreased significantly after treatment with insulin pump for 6 months, 8.97% ± 1.69% before treatment and 7.51% ± 1.17% (t = 2.52, P <0.05) after treatment. There was no significant decrease in insulin dosage; Hypoglycemia and ketoacidosis. Insulin pump therapy can effectively control blood sugar, significantly reduce HbA1c, reduce the incidence of hypoglycemia and ketoacidosis, T1DM children and adolescents is a better choice for conventional treatment.