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目的探讨重症手足口病患儿脑脊液的特点。方法对164例重症手足口病患儿入院后1~3 d的脑脊液检查结果进行分析,包括脑脊液常规、生化的测定数据。结果 164例重症患儿脑脊液细胞数、分类、生化在各年龄段比较差异无统计学意义,基本符合病毒性脑炎的脑脊液改变,个别患儿细胞数、脑脊液糖、蛋白定量明显升高。结论对重症手足口病患儿,尤其对伴有神经系统症状及体征表现的患儿应及早行脑脊液检查,此检查对病情、疗效和预后的评估有意义。
Objective To investigate the characteristics of cerebrospinal fluid in children with severe hand-foot-mouth disease. Methods 164 cases of severe HFMD children admitted to hospital 1-3 days after the cerebrospinal fluid test results were analyzed, including cerebrospinal fluid routine, biochemical data. Results The number, classification and biochemistry of cerebrospinal fluid in 164 cases of severe illness were not significantly different among all age groups. Cerebrospinal fluid (CSF) was found to be basically consistent with viral encephalitis. The number of cells and the contents of carbohydrate and protein in CSF were significantly increased. Conclusion Children with severe hand-foot-mouth disease, especially those with neurological symptoms and signs, should be treated with cerebrospinal fluid as early as possible. This examination is meaningful for the evaluation of disease, curative effect and prognosis.