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肝纤维化是肝硬化的早期阶段,是慢性肝病向肝硬化发展的必经途径,是各种慢性肝病的病理学共同基础。其主要病理特点是胶原蛋白、蛋白多糖及粘连糖蛋白等多种细胞外基质在肝内过度沉积。肝纤维化在进入肝硬化之前,尚有逆转至正常的可能,因此人们对肝纤维化的治疗十分重视。有云谁能阻止或减慢肝纤维化的发生,将会治愈大多数慢性肝病患者。本文简要综述近年来对肝纤维化治疗的一些新认识和新进展。
Liver fibrosis is an early stage of cirrhosis, is the only way to develop chronic liver disease to liver cirrhosis, is the common basis of pathology of various chronic liver diseases. The main pathological features of collagen, proteoglycan and adhesion glycoprotein and other extracellular matrix over-deposition in the liver. Liver fibrosis before entering the cirrhosis, there is still the possibility of reversing to normal, so people attach great importance to the treatment of liver fibrosis. There are clouds who can stop or slow down the occurrence of liver fibrosis, will cure most patients with chronic liver disease. This article briefly reviews some recent advances in the treatment of liver fibrosis.