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应用体积描记仪对１３４例不吸烟健康成年人和１６９例慢阻肺（ＣＯＰＤ）患者进行了气道阻力（Ｒａｗ）、气道传导率（Ｇａｗ）、比气道阻力（ｓＲａｗ）、比气道传导率（ｓＧａｗ）、胸腔气量（Ｖｔｇ）等测定。经多元回归统计出预计回归方程式，并依此公式对吸烟组、慢支组、肺气肿组、肺心病组实测值占预计值百分比均值作显著性比较，结果：吸烟组与正常组比较ｓＲａｗ、ｓＧａｗ相差非常显著（Ｐ＜０．０１）；Ｒａｗ、Ｇａｗ、Ｖｔｇ差异不显著（Ｐ＞０．０５）。与慢支、肺气肿、肺心病组与正常组比较除Ｖｔｇ相差显著（Ｐ＜０．０５）；Ｒａｗ、Ｇａｗ、ｓＲａｗ、ｓＧａｗ、Ｖｔｇ均相差非常显著（Ｐ＜０．００１）。表明：吸烟主要影响小气道，而单纯慢支的病变多限于小气道以上的支气管，肺气肿、肺心病时大小气道均受累的变化规律。
The airway resistance (Raw), airway conductance (Gaw), specific airway resistance (sRaw), specific airway Conductivity (sGaw), chest gas volume (Vtg) and other measurements. The regression equation was statistically calculated by multiple regression analysis, and significant differences were found between the measured values of the smoking group, the chronic bronchitis group, the emphysema group and the pulmonary heart disease group as a percentage of the predicted value according to the formula. Results: Compared with the normal group, , SGaw difference was significant (P <0.01); Raw, Gaw, Vtg difference was not significant (P> 0.05). Compared with Vtg in chronic bronchitis, emphysema and pulmonary heart disease group, the difference of Vtg was significant (P <0.05). The difference of Raw, Gaw, sRaw, sGaw and Vtg was significant (P <0.001). Show that: smoking mainly affects the small airways, and simple chronic bronchitis lesions are limited to more than the small airway bronchus, emphysema, pulmonary heart disease are involved in the size of the airway changes.