Synthesis and labelling of epidepride

来源 :核技术：英文版 | 被引量 : 0次 | 上传用户：nieguangyi127

【摘要】

：

S-(-)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-iodo-2,3-dimethoxybenzamide (proposed generic name, epidepride) is a very potent dopamine D2 antagonist. It was synth

【作者】

：

YANGMin PEIZhu－Guo 等

【机构】

：

StateKeyLaboratoryofNuclearMedicine

【出处】

：

核技术：英文版

【发表日期】

：

2001年2期

【关键词】

：

放射医学大脑神经同位标记 [131I]epidepride Dopamine D2 antagonist Synthesize Aryltin pre

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S-(-)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-iodo-2,3-dimethoxybenzamide (proposed generic name, epidepride) is a very potent dopamine D2 antagonist. It was synthesized by five steps from 3-methoxysalicylic acid. [131I]epidepride was obtained in 97.3％ radio

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Synthesis and labelling of epidepride

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