Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of cancer death globally, accounting for an estimated 1.2 million new c
DNA methylation plays an important role in cancer and is associated with gene silencing of tumour suppressor genes.The methylation of CpG sites is established b
Genomic amplification of oncogenes has been linked to increased expression associated with malignancy.Recent evidence suggests that increased copy numbers of re
Occurrence of multiple independent cancers in a tissue of an individual is known as field cancerization.Traditionally, accumulation of mutations in the tissue w