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目的:了解我院药品不良反应(ADR)发生的特点及引发ADR的相关因素,促进临床合理用药。方法:对我院2006～2010年收集的303例ADR报告进行回顾性分析。结果:303例ADR报告中,各年龄段均有分布,50岁以上的患者较多;给药途径以静脉给药为主,共235例(77.6%);抗微生物药139例(38.7%),其次是中药制剂58例(16.2%);皮肤及附件损害最多,有108例(28.7%)。结论:ADR发生与多种因素有关,应积极开展ADR监测工作,以减少或避免ADR的发生。
Objective: To understand the characteristics of adverse drug reaction (ADR) in our hospital and the related factors that lead to ADR, to promote clinical rational use of drugs. Methods: 303 cases of ADR collected in our hospital from 2006 to 2010 were analyzed retrospectively. Results: Of the 303 ADR cases, there were more than 50 years of age in all age groups. The route of administration was intravenous, with a total of 235 cases (77.6%) and antimicrobial drugs (139 cases, 38.7%). , Followed by 58 cases of traditional Chinese medicine preparation (16.2%); skin and accessories damage the most, 108 cases (28.7%). Conclusion: The occurrence of ADR is related to many factors. ADR monitoring should be actively carried out to reduce or avoid the occurrence of ADR.