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目的:对工业生产中不同商品规格三七总苷提取原料药的质量进行综合评价。方法:采用高效液相法测定3种商品规格原料药(剪口,120～200头,80～120头)中有效成分的含量,并经过相同的提取工艺后分别得到各三七总苷提取物,测定提取物中各有效成分的含量,并计算出膏率及有效成分转移率,综合评价3种商品规格原料药的优劣。结果:3种商品规格(剪口,120～200头,80～120头)原料药中人参皂苷Rg1和Rb1的含量分别为:4.98%和2.98%,2.81%和1.78%,2.67%和2.00%;三七总皂苷提取物中人参皂苷Rg1和Rb1的含量分别为:12.36%和7.48%,10.72%和6.57%,10.24%和7.51%;出膏率为分别39%,25%,25%;3种原料药中人参皂苷Rg1和Rb1的转移率分别为97%和98%,95%和92%,96%和94%。结论:3种商品规格的三七总苷提取原料中以剪口原料最优,120～200头和80～120头之间没有明显区别。
OBJECTIVE: To evaluate the quality of raw materials of Panax notoginseng extracted from different commercial products in industrial production. Methods: The HPLC method was used to determine the content of active ingredients in three kinds of commercial APIs (120 to 200 heads, 80 to 120 heads). After the same extraction process, the extracts of Panax notoginseng , The content of each active ingredient in the extract was measured, and the cream rate and active ingredient transfer rate were calculated, and the advantages and disadvantages of the three kinds of commercial APIs were comprehensively evaluated. Results: The contents of ginsenosides Rg1 and Rb1 in the three kinds of commercial products (notch, 120 ~ 200 heads and 80 ~ 120 heads) were 4.98% and 2.98%, 2.81% and 1.78%, 2.67% and 2.00% ; The content of ginsenosides Rg1 and Rb1 in Panax notoginseng saponins was 12.36% and 7.48%, 10.72% and 6.57%, 10.24% and 7.51%, respectively; The transfer rates of ginsenosides Rg1 and Rb1 in the three APIs were 97% and 98%, 95% and 92%, 96% and 94%, respectively. Conclusion: The optimal materials for the extraction of Panax notoginseng glycosides from the three commercial products are the best, with no significant difference between 120 to 200 heads and 80 to 120 heads.