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目的:分析磁共振-超声(MRI-US)图像融合引导下穿刺用于疑似淋巴瘤患儿的倾向性评分匹配性。方法:选择2015年4月至2020年4月郑州大学附属肿瘤医院收治的疑似淋巴瘤患儿276例。根据引导方法分为融合组(86例)和对照组(190例)。融合组予MRI-US图像融合引导下淋巴结粗针穿刺取活检；对照组予彩超引导下淋巴结粗针穿刺取活检。比较2组的一般资料、诊断率、淋巴瘤确诊率、病理类型和并发症发生率。结果:2组患儿经倾向性评分匹配后有80组配对成功，匹配后2组一般资料比较，差异无统计学意义(n P>0.05)。融合组的总诊断率、淋巴瘤诊断率和病理类型确诊率均高于对照组(97.50%、78.75%、96.25%比86.25%、63.75%、87.50%)，差异均有统计学意义(n χ2＝6.872、4.393、4.196，n P＝0.009、0.036、0.041)。融合组穿刺后并发症发生率低于对照组(5.00%比15.00%)，差异有统计学意义(n χ2＝4.444，n P＝0.035)。n 结论:采取MRI-US图像融合引导下肿块穿刺可提高淋巴瘤亚型的诊断率和淋巴瘤确诊率，并减少并发症的发生。“,”Objective:To evaluate the accuracy of mass puncture that is guided by magnetic resonance imaging-ultrasonography (MRI-US) image fusion when diagnosing lymphoma and lymphoma subtype among patients with suspected childhood lymphoma.Methods:A total of 276 suspected childhood lymphoma patients the Affiliated Cancer Hospital of Zhengzhou University from April 2015 to April 2020 were included.According to the methods of guidance before puncture and biopsied, they were classified into two groups.Totally, 86 patients were punctured and biopsied guided by the nuclear magnetic resonance imaging-ultrasonography (MRI-US) image fusion, and they were classified as “ fusion group” , while 190 patients guided by the color ultrasound were classified as “ control group” . Propensity score matching was applied to reduce the imbalance of covariates between the two groups.Diagnostic rate, lymphoma diagnosis rate, pathological type diagnosis rate, and complication rate were adopted to evaluate the accuracy of different guidance methods before puncture biopsy.Results:A total of 80 patients in each group were matched after propensity score matching, and the distribution of covariates between the two groups was balanced (n P>0.05). The total diagnosis rate, lymphoma diagnosis rate and pathological type diagnosis rate were higher in the fusion group (97.50%, 78.75%, and 96.25%) than those in the control group (86.25%, 63.75%, and 87.50%), and the differences were statistically significant (n χ2=6.872, 4.393, 4.196; n P=0.009, 0.036, and 0.041). The complication rate was lower in the fusion group than that in the control group (n χ2=4.444, n P=0.035), with 5.00% and 15.00%, respectively.n Conclusions:Mass puncture guided by MRI-US image fusion could improve the accuracy when diagnosing lymphoma and lymphoma subtype, and it could also reduce the relevant complication incidence.