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目的:探讨冠状动脉血栓抽吸术联合经皮冠状动脉介入术治疗急性心肌梗死合并冠状动脉血栓的疗效。方法:79例急性心肌梗死合并冠状动脉血栓患者,其中38例行急诊冠状动脉血栓抽吸术联合经皮冠状动脉介入术(治疗组),41例行择期经皮冠状动脉介入术(对照组)。比较2组急性期、术后1 a心脏事件发生率,病死率。结果:治疗组与对照组急性期心脏事件发生率分别为21.1%和34.1%,病死率分别为5.3%和9.7%,2组比较差异有统计学意义(P<0.01)。术后1 a治疗组与对照组心脏事件发生率分别为8.6%和13.9%,病死率分别为2.8%和5.5%,2组比较差异有统计学意义(P<0.01)。结论:急诊行冠状动脉血栓抽吸术联合经皮冠状动脉介入术治疗急性心肌梗死合并冠状动脉血栓安全、有效,对心功能的恢复,减少心脏事件和并发症的发生有重要意义。
Objective: To investigate the efficacy of coronary thrombus aspiration combined with percutaneous coronary intervention in patients with acute myocardial infarction complicated by coronary thrombosis. Methods: A total of 79 patients with acute myocardial infarction and coronary artery thrombosis were enrolled. Thirty-eight patients underwent emergency coronary thrombus aspiration and percutaneous coronary intervention, and 41 underwent elective coronary intervention (control group) . The incidence of cardiac events and mortality were compared between the two groups in acute stage and postoperative 1 year. Results: The incidences of acute cardiac events in the treatment group and control group were 21.1% and 34.1%, respectively, with mortality rates of 5.3% and 9.7% respectively. There was significant difference between the two groups (P <0.01). The incidences of cardiac events in the treated and control groups were 8.6% and 13.9%, respectively, with a mortality of 2.8% and 5.5%, respectively, after 1 year of treatment. The difference between the two groups was statistically significant (P <0.01). Conclusions: Emergency coronary artery thrombectomy combined with percutaneous coronary intervention for the treatment of acute myocardial infarction with coronary artery thrombosis is safe and effective, the recovery of cardiac function, reduce the incidence of cardiac events and complications of great significance.