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目的探讨血清降钙素原在ICU感染患者中的临床诊断价值。方法选取河池市人民医院ICU2014年1月—2016年1月收治的感染患者54例为研究1组,未感染患者54例为研究2组,另抽取同期健康体检的健康人54例为对照组,测定比较3组受试者的血清降钙素原、C反应蛋白水平及其阳性率。结果 3组受试者血清降钙素原、C反应蛋白水平比较,差异有统计学意义(P<0.05);其中研究1组和研究2组患者血清降钙素原、C反应蛋白水平高于对照组(P<0.05);研究1组患者血清降钙素原、C反应蛋白水平高于研究2组(P<0.05)。3组受试者血清降钙素原、C反应蛋白阳性率比较,差异有统计学意义(P<0.05);其中研究1组和研究2组患者血清降钙素原、C反应蛋白阳性率高于对照组(P<0.05);研究1组患者血清降钙素原、C反应蛋白阳性率高于研究2组(P<0.05)。结论 ICU中感染患者血清降钙素原、C反应蛋白水平异常升高,且其血清降钙素原、C反应蛋白阳性率也较高,可作为临床识别和筛选感染疾病的重要参考指标。
Objective To investigate the clinical value of serum procalcitonin in patients with ICU infection. Methods Fifty-four cases of infection in Hechi People’s Hospital ICU from January 2014 to January 2016 were selected as study group one, 54 cases of uninfected patients as study group 2, and 54 healthy individuals were selected as control group. Determination of serum procalcitonin, C-reactive protein levels and the positive rate of three subjects were compared. Results The levels of serum procalcitonin and C-reactive protein in the three groups were significantly different (P <0.05). The levels of serum procalcitonin and C-reactive protein in study group 1 and study group 2 were higher than those in study group 2 (P <0.05). The level of serum procalcitonin and C-reactive protein in study group 1 were higher than those in study group 2 (P <0.05). The positive rates of serum procalcitonin and C-reactive protein in the three groups were significantly different (P <0.05). The positive rates of serum procalcitonin and C-reactive protein in study group 1 and study group 2 were significantly higher (P <0.05). The positive rates of serum procalcitonin and C-reactive protein in study group 1 were higher than those in study group 2 (P <0.05). Conclusions The levels of serum procalcitonin and C-reactive protein in patients with ICU infection are abnormally elevated, and the positive rates of serum procalcitonin and C-reactive protein are also high, which may be used as an important reference for clinical identification and screening of infectious diseases.