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目的 研究体外循环围术期儿童与成人血浆皮质醇浓度的变化规律。方法 从手术前一天至手术后第四天,采取系列血样,测定血浆皮质醇浓度。结果 小儿组血浆皮质醇浓度在研究期内多数检测点上显著高于成人组。结论 提示小儿组手术中和手术后,应不用或慎用激素类药物。成人组应增加激素类药物的使用量。
Objective To study the changes of plasma cortisol concentrations in children and adults undergoing cardiopulmonary bypass. Methods From the day before operation to the fourth day after operation, a series of blood samples were taken to determine plasma cortisol concentration. Results The plasma cortisol concentration in pediatric group was significantly higher than that in adult group at most of the test points during the study period. The conclusions suggest that pediatric surgery and surgery should not or with caution hormone drugs. Adult group should increase the amount of hormonal drugs.