论文部分内容阅读
目的探讨孕产期颅内静脉栓塞的临床特点、发病因素，以及早期诊断、治疗的方法。方法回顾性分析１９８３年１月至１９９６年１２月我院收治的１８例孕产期颅内静脉栓塞患者的临床资料。结果全部病例均经ＣＴ检查确诊。１８例患者中，产前发病８例，产后发病１０例；合并妊高征１０例，有产后大出血史者８例；以头痛为主要症状者１３例，昏迷者１２例，频繁抽搐者８例，血液流变学检显示６例血液高凝；采用尿激酶治疗的１１例中，１０例痊愈，１例遗有共济失调。未治疗的６例中，３例痊愈，１例死亡，２例有后遗症。结论血液高凝与本病发生有关，频繁抽搐和昏迷是本病的主要特征；ＣＴ检查是极早确诊的重要手段；降颅内压抗凝消栓治疗，及时终止妊娠是该病的处理原则；尿激酶的早期使用可显示较好的治疗效果
Objective To explore the clinical features, pathogenesis, and the methods of early diagnosis and treatment of intracranial venous thrombosis during pregnancy and childbirth. Methods The clinical data of 18 pregnant women with intracranial venous thrombosis in our hospital from January 1983 to December 1996 were analyzed retrospectively. Results All cases were confirmed by CT examination. 18 cases of prenatal onset in 8 cases, 10 cases of postpartum onset; PIH complicated by 10 cases, with a history of postpartum hemorrhage in 8 cases; headache as the main symptom in 13 cases, coma in 12 cases, frequent convulsions in 8 cases , Hematological examination showed that 6 cases of blood hypercoagulability; Urokinase treatment of 11 cases, 10 cases recovered, 1 case left ataxia. Of the 6 untreated cases, 3 recovered, 1 died, and 2 had sequelae. Conclusions Blood hypercoagulability is related to the occurrence of this disease. Frequent convulsions and coma are the main features of this disease. CT examination is an important means of early diagnosis. Decreasing intracranial pressure anticoagulant suppressive therapy and timely termination of pregnancy are the principles of this disease Urokinase early use can show better therapeutic effect