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目的分析甲状腺乳头状癌细针穿刺细胞学(FNAC)特征。方法收集168例经组织病理学证实为甲状腺乳头状癌的FNAC标本,分析FNAC特征和术前超声影像学表现。结果 FNAC检查诊断为甲状腺乳头状癌的有148例;其中,145例见核沟,136例见核假包涵体,119例见乳头状结构,106例见毛玻璃样核,73例见多核巨细胞,58例见砂砾体。术前超声图像显示,结节区域多表现为不均匀低回声;其中,124例显示结节边缘不清晰或呈不规则粗糙毛刺状,58例结节内发现沙砾体样钙化灶。结论核沟、核假包涵体、乳头状结构、毛玻璃样核、多核巨细胞、砂砾体等是FNAC诊断甲状腺乳头状癌的重要指标。将FNAC特点与超声影像学特征相结合对甲状腺乳头状癌的术前诊断具有重要意义。
Objective To analyze the characteristics of fine needle aspiration cytology (FNAC) in papillary thyroid carcinoma. Methods A total of 168 FNAC specimens confirmed by histopathology as papillary thyroid carcinoma were collected and analyzed for FNAC features and preoperative ultrasound imaging findings. Results There were 148 cases diagnosed as papillary thyroid carcinoma by FNAC. Among them, 145 cases were found to have nuclear ditch, 136 cases were nuclear fusiform inclusion bodies, 119 cases were papillary structures, 106 cases were smegma-like nuclei, 73 cases were multinucleated giant cells , 58 cases see gravel. Preoperative ultrasound images showed nodular regions showed uneven hypoechoic; 124 cases showed unclear nodules or irregular rough burr-like, 58 cases of nodules found gravel-like calcification. Conclusion The nuclear ditch, nuclear fusiform inclusion, papillary structure, frosted vitreous nucleus, multinucleated giant cell, grit and so on are important indexes for the diagnosis of papillary thyroid carcinoma by FNAC. The combination of FNAC features and ultrasound imaging features is of great importance for the preoperative diagnosis of papillary thyroid carcinoma.