外阴硬化性苔癣(VLS)以外阴搔痒、性交痛及外阴烧灼感为临床特点,晚期外阴多部位萎缩,有发展为外阴癌的趋势。近年国内外学者对VLS的病因及发病机制进行了大量深入的研究,认为外阴硬化性苔癣的发生与遗传、免疫、局部微环境及信号转导等多种因素有关,且对VLS的临床治疗包括药物治疗和物理治疗也进行了广泛的探索,取得了一定的进展。 Vulvar vulgaris (VLS) genital itching, painful sexual intercourse and vulvar burning as a clinical feature, multiple parts of the late atrophy of the vulva, the trend for the development of vulvar cancer. In recent years, domestic and foreign scholars have done a great deal of deep research on the etiology and pathogenesis of VLS. They think that the occurrence of vulvar vulgaris is related to many factors such as heredity, immunity, local microenvironment and signal transduction, and the clinical treatment of VLS Including drug treatment and physical therapy have also been extensive exploration and made some progress.