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目的观察硝普钠与参麦注射液联合治疗充血性心力衰竭的临床疗效。方法充血性心力衰竭62例随机分为治疗组32例,对照组30例。对照组给予病因治疗、利尿剂、血管紧张素转换酶抑制剂、醛固酮系统拮抗剂和洋地黄类药物治疗,治疗组在上述治疗的基础上静脉应用硝普钠和参麦注射液,硝普钠用药时间(96±72)h,10 d为1个疗程进行比较。结果对照组的总数效果为73%,治疗组为97%,两组比较差异有统计学意义(P<0.05);治疗组治疗后心率、左室射血分数(LVEF)较对照组改善明显,两组比较差异也有统计学意义(P<0.05)。结论硝普钠与参麦注射液联合治疗充血性心力衰竭安全有效,可进一步改善心功能。有“标本兼治”的作用。
Objective To observe the clinical efficacy of sodium nitroprusside and shenmai injection in the treatment of congestive heart failure. Methods Sixty-two patients with congestive heart failure were randomly divided into treatment group (n = 32) and control group (n = 30). The control group was given etiological treatment, diuretics, angiotensin converting enzyme inhibitors, aldosterone system antagonists and digitalis drugs, the treatment group on the basis of the above treatment, intravenous sodium nitroprusside and shenmai injection, sodium nitroprusside drug Time (96 ± 72) h, 10 d for a course of treatment were compared. Results The total effect of the control group was 73%, the treatment group was 97%, the difference between the two groups was statistically significant (P <0.05); after treatment, the treatment group, heart rate, left ventricular ejection fraction (LVEF) improved significantly compared with the control group, The difference between the two groups was also statistically significant (P <0.05). Conclusion Sodium nitroprusside and shenmai injection combined with congestive heart failure is safe and effective, which can further improve cardiac function. Have “role model ” role.