在我院血液科举办的血液系统疾病诊疗新进展学习班上,分享了1例淋巴浆细胞淋巴瘤(lymphoplasmacytic lymphoma,LPL)的病例。LPL/华氏巨球蛋白血症(Waldenstrm’s macroglobulinemia,WM)缺乏与其他伴有浆细胞分化的成熟小B细胞淋巴瘤相鉴别的特异性形态学、免疫表型、基因及临床特征。就目前的诊断标准而言,WM与Ig M型意义未明的单克隆γ病和边缘区淋巴瘤(MZL)在诊 A case of lymphoplasmacytic lymphoma (LPL) was shared in the New Course of Hematological Disease Diagnosis and Treatment held by Department of Hematology in our hospital. LPL / Waldenstrm’s macroglobulinemia (WM) lacks specific morphological, immunophenotypic, genetic, and clinical features that are differentiated from other mature small B cell lymphomas with plasma cell differentiation. For the current diagnostic criteria, WM and Ig M-type monoclonal gammas of unknown significance and marginal zone lymphoma (MZL)