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目的采用前瞻性随机对照研究,以乳腺癌术后化疗患者为研究对象,探讨心理社会干预对其生存质量的影响。方法120例病人被随机分配到干预组(60例)和对照组(60例),干预组除常规药物治疗外,接受系统的心理社会干预,如健康教育、放松训练及集体心理干预,对照组只有药物治疗。采用中国癌症化疗患者生活质量量表(QLQ-CCC)及症状自评量表(SCL-90)作为乳腺癌化疗患者生存质量和心理状况的测查指标。结果乳腺癌化疗患者的生存质量状况以化疗中最差,而治疗结束后,干预组患者的SCL-90总分(131.9±13.7)与对照组(192.5±15.4)相比,P<0.01;而躯体、心理、社会、总体方面评分分别为:26.7±2.6分、13.7±1.5分、8.5±0.8分、46.9±3.5分,P<0.05或0.01,表明干预组患者的不良情绪明显改善,生存质量明显提高。结合对乳腺癌术后化疗患者实施系统的心理社会干预,是改善不良情绪,提高生存质量的有效方法之一,值得推广应用。
Objective To investigate the impact of psychosocial intervention on the quality of life of prospective breast cancer patients treated with chemotherapy after a prospective randomized controlled trial. Methods A total of 120 patients were randomly assigned to the intervention group (60 cases) and the control group (60 cases). The intervention group received psychosocial interventions such as health education, relaxation training and collective psychotherapy, while the control group Only medical treatment. The QLQ-CCC and SCL-90 were used as indicators of quality of life and psychological status in patients with breast cancer who underwent chemotherapy. Results The quality of life of breast cancer patients under chemotherapy was the worst in chemotherapy. After treatment, the score of SCL-90 in intervention group (131.9 ± 13.7) was significantly lower than that of control group (192.5 ± 15.4) (P <0.01) The physical, psychological, social and overall scores were 26.7 ± 2.6 points, 13.7 ± 1.5 points, 8.5 ± 0.8 points and 46.9 ± 3.5 points respectively, P <0.05 or 0.01, indicating that the bad mood in the intervention group was significantly improved and the quality of life Significantly improved. The combination of psychotherapy and social intervention in patients with postoperative chemotherapy for breast cancer is one of the effective ways to improve the bad mood and improve the quality of life, which is worth popularizing and applying.