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目的探讨美托洛尔与非洛地平治疗单纯性收缩期高血压老年患者的临床疗效。方法收集本院2012年8月至2014年8月收治的单纯性收缩期高血压老年患者资料142例,将患者采用随机数字表法分为对照组与试验组,各71例,对照组患者给予美托洛尔,试验组患者给予非洛地平,比较两组患者的血压水平及不良反应情况。结果试验组患者治疗后舒张压、收缩压明显低于对照组,差异均有统计学意义(均P<0.05);两组患者不良反应比较,差异无统计学意义(P>0.05)。结论非洛地平对单纯性收缩期高血压患者收缩压具有明显的改善作用,更适宜应用于该疾病治疗。
Objective To investigate the clinical efficacy of metoprolol and felodipine in elderly patients with isolated systolic hypertension. Methods A total of 142 elderly patients with simple systolic hypertension were enrolled from August 2012 to August 2014 in our hospital. The patients were divided into control group and trial group by random number table, each of 71 patients in control group Metoprolol, the test group was given felodipine, blood pressure levels and adverse reactions were compared between the two groups. Results After treatment, the diastolic blood pressure and systolic blood pressure in the experimental group were significantly lower than those in the control group (all P <0.05). There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion Felodipine has a significant improvement on systolic blood pressure in patients with isolated systolic hypertension and is more suitable for the treatment of this disease.