早期幽门螺杆菌移植与生长发育迟滞的相关性:一项在冈比亚的研究

来源 :世界核心医学期刊文摘(儿科学分册) | 被引量 : 0次 | 上传用户:beauty85123
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Background: Helicobacter pylori is one of the commonest causes of chronic infection of mankind, yet the natural history of acute infection is poorly understood. Some studies suggest that gastric colonisation with H pylori is associated with suboptimal nutrition and growth in childhood. Aims: To describe the clinical features of early H pylori colonisation and assess its role in the development of infant malnutrition and growth faltering. Methods: Two consecutive prospective longitudinal cohort studies were conducted at the Medical Research Council Laboratories in a rural community in The Gambia,West Africa. The first birth cohort of 125 infants was followed by a second of 65 children from the same community. H pylori colonisation was detected by sequential 13C urea breath tests, and infant growth was monitored by serial measurements. Results: Children with early H pylori colonisation became significantly lighter, shorter, and thinner than their peers in late infancy. The association was found in both cohorts. No socioeconomic or demographic confounding variables were identified to explain this, and the weight deficit was no longer detectable when the children were aged 5-8 years. Conclusions: Results suggest that H pylori colonisation in early infancy predisposes to the development of malnutrition and growth faltering, although the effect did not persist into later childhood. Background: Helicobacter pylori is one of the commonest causes of chronic infection of mankind, yet the natural history of acute infection is poorly understood. Some studies suggest that gastric colonization with H pylori is associated with suboptimal nutrition and growth in childhood. Aims: To describe the clinical features of early H pylori colonization and assess its role in the development of infant malnutrition and growth faltering. Methods: Two consecutive prospective longitudinal cohort studies were conducted at the Medical Research Council Laboratories in a rural community in The Gambia, West Africa. First birth cohort of 125 infants was followed by a second of 65 children from the same community. H pylori colonization was detected by sequential 13C urea breath tests, and infant growth was monitored by serial measurements. Results: Children with early H pylori colonisation was significantly lighter, shorter, and thinner than their peers in late infancy. The association wa s found in both cohorts. No socioeconomic or demographic confounding variables were identified to explain this, and the weight deficit was no longer detectable when the children were aged 5-8 years. Conclusions: Results suggest that H pylori colonization in early infancy predisposes to the development of malnutrition and growth faltering, although the effect did not persist into later childhood.
其他文献
科学证实,人在不吃不喝的情况下,生命能维持一周,那么,一旦没有了氧气,恐怕连10分钟都不用了就会窒息而死。但是我们在印度却见到了一些神奇的瑜伽师,他们不吃不喝,甚至把他
很多学生进入高中以后,对物理的学习仍然沿用初中物理的学习方法。一段时间以后,发现自己并不能像初中那样取得满意的成绩;究其原因就是没有注意到初高中物理之间的异同。现
散文大师秦牧与图书馆陈章庭(澄海县图书馆)我国著名作家、散文大师秦牧与澄海图书馆的密切缘份。1991年10月,我县举办《海内外澄籍人士(部分)著作》展览。筹展组为了搜集到更多的著作,专
乳糖醇(乳梨醇)的英文名Lactitol,它是以乳糖为原料经还原制得的二元糖醇,可作为低热值、防龋齿的代糖品,味甜适口。乳糖醇近年来在国外发展迅猛,仅1985年至1995年欧美就有
瑞丽,这座小城就象它的名字一样美丽。它吸引人的地方很多。就气候而言,它属于亚热带气候,有著名的热带雨林风光;就区位而言,它与缅甸接壤,是祖国边境和国家级口岸。当然,这
2010年9月13日《书刊报》第4版刊登《叶剑英爱戴下属》一文,讲述了新中国开国元勋叶剑英元帅关爱身边工作人员的感人故事,让人备感亲切。但标题中“爱戴”一词无疑用错了。爱
任课教师应先明确认识到班主任在全班的影响力。班主任工作做得好,班级向心力强,班风正,学风浓,对任课教师的教学工作有很好的促进作用,使任课教师教学工作轻松自如、游刃有
又是一年桃花开。当涂县08’护河园艺桃花节正在举办。护河镇园艺村座落在当涂县大青山脚下,山那边就是唐代大诗人李白墓园。全村有果树近万亩,其中桃树占60%,另有梨树、柿树
3月10日,2012年新赛季中超盛大开幕!16支俱乐部,30亿投入!中国足球步入了一个前所未有的“金元中超”時代。巨额的投入,甚至可以说不输给任何一个顶级的欧洲联赛,就在这个春寒料峭的日子里,新赛季点燃了中国足迷久违的狂热与激情……    恒大模式开创先河     就在中超联赛开幕的前夜,中国广州恒大队在亚冠联赛中客场5:1痛击韩国劲旅全北现代队。在最初的那一刻,许多球迷以为自己搞错了比分,这是
今年3月,北京威猛机械制造有限公司在上海展览中心举行的2006年亚洲非开挖技术展览会暨研讨会上举行了一个简单而隆重的产品发布会。北京威猛机械制造有限公司是美国威猛旗下