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研究发现,当机体摄入过量的砷及其化合物时,可对机体造成多种系统的严重氧化损伤,进而严重威胁人类健康,而砷及其化合物所致机体内生物大分子氧化损伤被认为是砷中毒的重要作用机制~([1])。研究发现,龙眼参多糖对氟中毒大鼠的机体抗氧化能力起到了保护作用,降低氟中毒对机体的氧化损伤作用~([2])。但是关于龙眼参多糖对砷中毒所致的氧化损伤的相关作用尚未见报道。本研究通过复制砷中毒肝损伤小鼠模型,观察小鼠肝组织中MDA、SOD、GSH和GSH-PX
The study found that when the body intake of excessive amounts of arsenic and its compounds, the body can cause a variety of serious oxidative damage system, and thus a serious threat to human health, and arsenic and its compounds induced by biological macromolecules oxidative damage is considered to be Arsenic poisoning an important mechanism of action ~ ([1]). Study found that longan ginseng polysaccharide on fluorosis in rats antioxidant capacity has played a protective effect, reduce fluoride poisoning on the body’s oxidative damage ~ ([2]). However, the role of longan polysaccharides on oxidative damage caused by arsenic poisoning has not been reported. In this study, arsenic poisoning liver injury mouse model was duplicated to observe the changes of MDA, SOD, GSH and GSH-PX