本文观察了141例急型和亚急型克山病尸检病例肝脏的形态学改变,并与死于休克或心力衰竭的非克山病病例肝脏病变进行了比较。结果发现,三者在病变性质上无明显区别,但克山病组肝脏坏死检出率则高于其它两组,其中与心力衰竭组相比,已经达到显著差异的程度(P<0.05)。认为克山病肝脏坏死性改变是由其病因所造成的原发性肝脏损伤与休克及心力衰竭等缺氧因素共同作用的结果。 In this paper, morphological changes of liver in 141 cases of acute and subacute Keshan disease autopsy were observed and compared with those of non-Ketosis cases in shock or heart failure. The results showed that there was no significant difference in the nature of the lesions between the three groups. However, the detection rate of liver necrosis in Keshan disease group was higher than that in the other two groups, which was significantly different from that in the heart failure group (P <0.05). Keshan disease that changes in liver necrosis is caused by the etiology of primary liver injury and shock and heart failure and other hypoxia caused by the combination of the results.