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目的：研究血清可溶性白细胞介素2受体（sIL-2R）水平在检查乙肝病毒不同类型感染中的意义。方法：应用ELISA方法检测42例正常人及228例乙肝病毒感染者血清中sIL－2R水平。并从感染者中筛选出3组进行比较，A组（大三阳，HBsAg，HBcAb，HBeAg（＋））；B组（小三阳，HBsAg，HBcAb，HbeAb（＋））；C组（HBsAg（＋））。结果：228例感染者血清中sIL－2R水平较正常人都明显增高（P＜0．01）。且A，B两组sIL－2R水平与正常人相比也差异显著（P＜0．05）。各组之间比较，仅A与C组之间有显著差异（P＜0．01）。结论：提示检测血清中sIL－2R可作为乙肝病毒感染者病情变化和预后判断的监测指标。
Objective: To investigate the significance of serum soluble interleukin-2 receptor (sIL-2R) in detecting different types of hepatitis B virus infection. Methods: The serum levels of sIL-2R in 42 normal subjects and 228 patients with hepatitis B virus infection were detected by ELISA. The three groups were selected from the infected group for comparison. Group A (HBsAg, HBsAg, HBeAb, HBeAg (+)), B group (HBMSAg, HBcAb, HbeAb +)). Results: The levels of sIL-2R in 228 infected patients were significantly higher than those in normal controls (P <0.01). The sIL-2R levels in groups A and B were also significantly different from those in normal controls (P <0.05). There was significant difference between groups A and C (P <0.01). Conclusion: It is suggested that the detection of sIL-2R in serum can be used as the monitoring index for the change of disease and prognosis in patients with hepatitis B virus infection.