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目的:探讨血清胱抑素C(Cyc C)测定在肾功能早期损伤诊断中的价值。方法:运用随机抽样的方法选取我院2013年1月至2014年9月收治的63例肾功能早期损伤患者,依据实际病情分为五组,将这些患者作为研究组,另选取同期来我院进行健康体检的51例健康人员作为对照组,采用上海丰汇科技股份有限公司生产的试剂盒对各组人员的Cyc C进行测定,采用北京利德曼有限公司生产的试剂盒对各组人员的尿素氮、Scr水平进行测定。结果:研究组患者的Cyc C、尿素氮、Scr水平均显著高于对照组(P<0.05);研究组患者随着肾功能早期损伤程度的加重,血清Cyc C、尿素氮水平均逐渐升高(P<0.05)。结论:Cyc C测定在肾功能早期损伤诊断中具有较高的临床应用价值。
Objective: To investigate the value of serum Cystatin C in the diagnosis of early renal injury. Methods: Sixty-three patients with early renal injury who were admitted to our hospital from January 2013 to September 2014 were randomly divided into five groups according to their actual condition. The patients were selected as the study group. 51 healthy people who took physical examination were taken as the control group, and the Cyc C of each group was determined by the kit produced by Shanghai Fenghui Science and Technology Co., Ltd. The kit of each group was tested by the Kit manufactured by Beijing Leadman Co. Urea nitrogen, Scr levels were measured. Results: The levels of Cyc C, urea nitrogen and Scr in the study group were significantly higher than those in the control group (P <0.05). In the study group, the levels of Cyc C and urea nitrogen increased gradually with the increase of early renal injury, (P <0.05). Conclusion: Cyc C assay has high clinical value in the diagnosis of early renal damage.