铁蛋白是体内铁贮存的主要形式之一,并可能主动地参与铁的代谢过程.在一些恶性肿瘤病人,血清铁蛋白含量明显增高.近年来的研究发现,铁蛋白存在着很多异质体即同工铁蛋白(I soferritin s),在不同的病理情况下,升高的铁蛋白的种类不同.在恶性肿瘤时,增高的铁蛋白主要为酸性铁蛋白,在等电聚焦实验中,表现为较低的等电点(PI)值.进一步的研究发现,酸性铁蛋白增多,与原发性肝癌之间有着密切的关 Ferritin is one of the main forms of iron storage in the body, and may actively participate in the metabolic process of iron. In some patients with malignant tumors, serum ferritin content increased significantly. Recent studies have found that ferritin has a lot of heteroplasmic Isoferritin s, under different pathological conditions, has different ferritin types. In malignant tumors, the elevated ferritin is mainly acidic ferritin, and in isoelectric focusing experiments, it is shown as Lower isoelectric point (PI) values. Further studies have found that the increase in acid ferritin is closely related to primary liver cancer.