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目的:探讨宫颈锥切术中冰冻病检在宫颈高度病变诊治中的应用价值。方法:对经多点活检确诊为宫颈上皮内瘤变Ⅲ级/原位癌(CINⅢ/CIS)并行冷刀宫颈锥切术中宫颈标本快速冰冻病检的138例患者的资料进行回顾性分析,比较所有患者冰冻及手术前后组织病理结果的差异。结果:138例患者中,120例(86.96%)术中冰冻与术后石蜡结论一致,18例不符,其中3例冰冻为CIS,石蜡为浸润癌;4例冰冻可疑浸润癌,石蜡2例为CIS,2例为浸润癌;1例冰冻为慢性炎症,术后发现有CINⅡ;3例冰冻为CINⅡ,石蜡2例为CINⅢ,1例为CIS;1例冰冻为CINⅠ,术后为CINⅢ;另有3例冰冻为CINⅢ,石蜡为CIS,3例冰冻为CIS,石蜡为CINⅢ。结论:术中冰冻对宫颈高度病变的诊断有一定的误差,临床应用需慎重。
Objective: To investigate the value of frozen pathology in the diagnosis and treatment of cervical lesions during cervical conization. Methods: The retrospective analysis of 138 patients diagnosed as cervical intraepithelial neoplasia (CINⅢ / CIS) complicated by cold knife cervical conization under multipoint biopsy was performed. All patients were compared between frozen and histopathological differences before and after surgery. Results: Of the 138 patients, 120 cases (86.96%) had the same postoperative paraffin as the postoperative paraffin, which was inconsistent with 18 cases. Among them, 3 cases were frozen with CIS and paraffin was invasive carcinoma; 4 cases were suspected with frozen invasion and 2 cases with paraffin CIS, 2 cases of invasive carcinoma; 1 case of chronic inflammation, found after surgery CIN Ⅱ; 3 cases of frozen CIN Ⅱ, paraffin 2 cases of CIN Ⅲ, 1 case of CIS; 1 case of frozen CIN Ⅰ, postoperative CIN Ⅲ; There were 3 cases of frozen CIN Ⅲ, paraffin for the CIS, 3 cases of frozen CIS, paraffin wax CIN Ⅲ. Conclusion: Intraoperative freezing has a certain error in the diagnosis of cervical lesions, the clinical application of caution.