论文部分内容阅读
目的:探讨鼻腔鼻窦炎性肌纤维母细胞瘤(IMT)的临床特点、治疗方法及疗效。方法:回顾性分析经病理确诊的鼻腔鼻窦炎性肌纤维母细胞瘤14例患者的临床资料,其中手术治疗12例,手术并术后辅助放疗2例。结果:随访1~7年,术后2例经病理检查证实为低度恶性IMT。至末次随访,8例预后良好,6例复发,其中4例死亡,2例带瘤生存。结论:IMT很少见,诊断主要依靠病理及免疫组织化学检测。正确的诊断很有必要,以避免破坏性或毁容手术。手术彻底切除仍为目前首选的治疗方法,放化疗的作用有待进一步探讨。该病术后复发率较高,需长期随访。
Objective: To investigate the clinical features, treatment and efficacy of nasal sinusitis myofibroblastoma (IMT). Methods: The clinical data of 14 patients with pathologically diagnosed rhinosinusitis myofibroblastoma were retrospectively analyzed. Among them, 12 cases were treated by surgery and 2 cases received postoperative adjuvant radiotherapy. Results: Followed up for 1 to 7 years and 2 cases postoperatively confirmed as low grade IMT by pathological examination. To the last follow-up, 8 patients had a good prognosis, 6 patients relapsed, 4 patients died and 2 patients survived. Conclusion: IMT is rare, the diagnosis mainly depends on pathology and immunohistochemistry. Correct diagnosis is necessary to avoid damaging or disruptive operations. Radical resection is still the preferred method of treatment, the role of radiotherapy and chemotherapy remains to be further explored. The postoperative recurrence rate is high, requiring long-term follow-up.