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尽管没有任何一种抗疟药能够既有效地预防疟疾感染又保证绝对安全,但是预防疟疾的药物仍起着十分重要的作用。近十年来英国疟疾病例显著增加的原因之一就在于原虫对预防药物产生了抗性,以及这些药物众多的副反应限制了它们的使用。目前仅有少数药物如氯喹、氯胍、盐酸甲氟喹和Maloprim(乙胺嘧啶/氨苯砜)用于疟疾预防。法西达常引起血液病、皮肤反应和Stevens-Johnson综合征,阿莫地喹可引起粒细胞减少、肝脏损害,因此均已不再作为预防药物。氯喹每周300mg用于预防几乎不出现问题,但常发生过敏性胃肠不适,有时还发生
Although no anti-malarial drug can effectively prevent malaria infection and ensure absolute safety, drugs for preventing malaria still play an important role. One of the reasons why there has been a significant increase in malaria cases in the UK in the last decade is that protozoa are resistant to prophylactic drugs and the numerous side effects of these drugs limit their use. Only a few drugs such as chloroquine, proguanil, mefloquine hydrochloride and Maloprim (pyrimethamine / dapsone) are currently used for malaria prevention. Farnesa often causes hematological disorders, skin reactions and Stevens-Johnson syndrome. Amodiaquine can cause neutropenia and liver damage and is no longer used as a preventive drug. Chloroquine 300mg weekly for the prevention of almost no problems, but often occurs in allergic gastrointestinal discomfort, and sometimes also occurs