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在不久的将来可对易患膀胱癌的人进行鉴别,避免从事具有潜在危害性的职业。在英国利兹的研究工作是对于肝结合酶族N—乙酰转移酶的意义的研究,已经历过一个时期。这种酶族与引起膀胱癌物质的解毒有关。所以,如果这一酶族有缺损或作用缓慢,则不能通过乙酰化而使致癌物解毒。乙酰化的速率,人各不同,可分为“迅速”乙酰化或“缓慢”乙酰化两类人。这是由遗传决定的。对膀胱癌患者和相同数量的对照组检测了乙酰化的情况。并将病人的职业史与
In the near future, it is possible to identify people who are susceptible to bladder cancer and avoid engaging in potentially harmful occupations. Research in Leeds, UK, has been a study of the significance of the liver-associated enzyme family N-acetyltransferase. This family of enzymes is involved in the detoxification of bladder cancer substances. Therefore, if this enzyme family is defective or has a slow effect, carcinogens cannot be detoxified by acetylation. The rate of acetylation varies from person to person and can be divided into two categories: “rapid” acetylation or “slow” acetylation. This is genetically determined. Acetylation was detected in patients with bladder cancer and the same number of controls. And the patient’s professional history