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镁对心脏病有一定治疗作用。动物实验表明,镁浓度下降会导致心律失常,冠状动脉痉挛以及因儿茶酚胺释放使心肌坏死的机会增加等。在人体,低镁常伴发心律失常,心功能不全以及缺血性心脏猝死。急性心肌梗塞(AMI)患者血清镁浓度(S-Mg)可能指时性(通常少于48小时)下降,也可能一直正常。从AMI病人尸解中获得的心肌组织中镁浓度也低。于是作者采用双盲法研究了AMI病人静注镁的作用, 本研究包括入院时怀疑AMI的273例病人,随机分为镁治疗组织和安慰剂一对照组。前者137例,后者136例。最后确诊为AMI共130例,镁治疗组56例,对照组74例。镁治疗组男39例,女17例,70以下37例,≥70岁19例,既往有心脏病者28例;对照组男43例,女31例,70岁以下42例,≥70岁32例,既往有心脏病者32例。镁治疗组入院后头
Magnesium has a certain therapeutic effect on heart disease. Animal experiments show that magnesium concentration decreased lead to arrhythmia, coronary spasm and catecholamine release of myocardial necrosis opportunities. In the human body, low magnesium often accompanied by arrhythmia, cardiac insufficiency and ischemic sudden cardiac death. Serum magnesium concentration (S-Mg) in patients with acute myocardial infarction (AMI) may be indicative of a decline in timeliness (usually less than 48 hours) or may remain normal. Magnesium concentrations in myocardial tissue obtained from the autopsy of AMI patients are also low. The authors then studied the role of magnesium in patients with AMI by a double-blind method. The study included 273 patients with suspected AMI at admission who were randomized to either magnesium-treated tissue or a placebo-controlled group. The former 137 cases, the latter 136 cases. The final diagnosis of AMI were 130 cases, 56 cases of magnesium treatment group, 74 cases of control group. There were 39 males and 17 females in the magnesium treatment group, 37 cases were less than 70 years old, 19 cases were ≥70 years old, 28 cases had heart disease in the past, 43 males and 31 females, 42 cases under 70 years old, ≥70 years old 32 For example, there are 32 cases of heart disease in the past. Magnesium treatment group after admission head