目的　探讨骨样骨瘤的病因、发病机制、临床特点以及临床诊治方法。方法　总结 1993 - 1999年收治的骨样骨瘤 13例 ,其中男 9例 ,女 4例 ,平均 2 1.5岁。发病部位为股骨颈 3例、股骨 5例、胫骨 3例、肱骨 1例、尺骨 1例。全部病例均行病巢切除术。结果　全部病例术后均经病理证实为骨样骨瘤 ,术后症状即消失 ,随访 1～ 6a无一例复发。结论　该瘤以疼痛尤其夜间痛为特征 ,其疼痛可能为瘤巢内前列腺素E2 增高所致 ,彻底切除瘤巢是治疗的关键 ,提倡精确定位的微创手术 Objective To investigate the etiology, pathogenesis, clinical features, and clinical diagnosis and treatment of osteoid osteoma. METHODS: Thirteen cases of osteoid osteoma were treated from 1993 to 1999, including 9 males and 4 females, with an average age of 21.5 years. The site of the disease was 3 cases of femoral neck, 5 cases of femur, 3 cases of sacrum, 1 case of sacrum, and 1 case of ulna. All cases underwent disease nest resection. Results All cases were proved to be osteoid osteoma by pathology after operation. The symptoms disappeared after operation. No recurrence occurred during the follow-up of 1 to 6 years. Conclusion The tumor is characterized by pain, especially nocturnal pain. The pain may be due to the increase of prostaglandin E2 in the tumor nest. Thorough resection of the tumor nest is the key to treatment, and it advocates accurate positioning of minimally invasive surgery.