论文部分内容阅读
作者利用免疫组化LSAB法和流式细胞分析技术(FCM)对41例进展期胃癌组织中增殖细胞核抗原(PCNA)的表达及细胞核DNA含量进行了测定。结果表明:PCNA标记指数及DNA非整信体检出率与胃癌病人术后5年生存率呈明显负相关(P<0.05),与淋巴结转移呈正相关(P<0.05)。DNA非整信体检出率与PCNA标记指数具有良好的相关性,二者均可用于判断胃癌预后,而二者同时运用则更有参考价值。
The authors used immunohistochemistry LSAB method and flow cytometric analysis (FCM) to determine the expression of proliferating cell nuclear antigen (PCNA) and nuclear DNA content in 41 cases of advanced gastric cancer. The results showed that the PCNA labeling index and DNA non-integrated body detection rate were significantly negatively correlated with postoperative 5-year survival rate of gastric cancer patients (P<0.05), and positively correlated with lymph node metastasis (P<0.05). There is a good correlation between DNA non-integrated body detection rate and PCNA labeling index, both of which can be used to determine the prognosis of gastric cancer, and the simultaneous use of the two is more valuable.