目的：探讨肝硬变患者医院感染的临床特点及防治对策。方法：对８９４例肝硬变患者的医院感染情况进行回顾性调查和分析。结果：医院感染率为１０．４０％，感染部位多见于消化系统（３９．２１％）和呼吸系统（３７．２５％），感染的细菌以Ｇ－杆菌为主。致危因素为老年、并发肝昏迷、上消化道出血或腹水、血浆白蛋白＜２５ｇ／Ｌ等。结论：健全医院感染监测网、选择敏感杀菌剂为防治肝硬变患者医院感染的有效对策 Objective: To investigate the clinical characteristics and prevention and treatment of nosocomial infection in cirrhotic patients. Methods: The 894 cases of cirrhosis patients with nosocomial infections were retrospectively investigated and analyzed. Results: The hospital infection rate was 10.40%. The infection site was more common in the digestive system (39.21%) and the respiratory system (37.25%). The infected bacteria were mainly G-bacilli. Risk factors for the elderly, complicated by hepatic coma, upper gastrointestinal bleeding or ascites, plasma albumin <25g / L and so on. Conclusion: To improve the hospital infection monitoring network, select a sensitive fungicide for the prevention and treatment of cirrhosis patients with nosocomial infections effective countermeasures