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目的 探讨彩色多普勒超声对肾病综合征 (NS)的肾血流动力学改变特征及病理类型间的关系。方法 将临床诊断、肾穿病理证实的 6 9例系膜增生性肾炎的病人 ,根据病理分轻、中、重三组 ,并与正常健康者 4 0例为对照组比较 ,观察肾段动脉、叶间动脉的收缩期最大流速 (Vs)、舒张期末速度 (Vd)、平均速度 (Vm)、搏动指数(PI) ,阻力指数 (RI)参数。结果 NS病人的肾段动脉、叶间动脉的 Vs、 PI、 RI出现显著性差异 (P<0 .0 1、 P<0 .0 5 ) ,但在病理各分型中血流差异不明显。结论 彩超对 NS病人的肾血流改变特点和估测病情变化、预后提供了一条无创性的辅助检测手段
Objective To investigate the relationship between renal hemodynamics and pathological changes of nephrotic syndrome (NS) by color Doppler sonography. Methods Sixty-nine patients with mesangial proliferative glomerulonephritis diagnosed clinically and with renal pathology were divided into three groups according to pathology: mild, moderate and severe, and compared with 40 normal controls. The renal artery, The maximum systolic velocity (Vs), end diastolic velocity (Vd), mean velocity (Vm), pulsatility index (PI) and resistance index (RI) Results There were significant differences in Vs, PI and RI between the renal arteries and interlobar arteries in NS patients (P <0.01, P <0.05), but there was no significant difference in the blood flow among various pathological types. Conclusion Color Doppler ultrasonography of NS patients with renal blood flow changes in the characteristics and assessment of disease progression, prognosis provides a non-invasive auxiliary means of detection