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糖尿病肾病(DN)是一常见的糖尿病慢性微血管并发症,给人类造成极大危害,目前尚无有效防治措施,因此关于DN发病机理的研究已成为热点。本实验建立了大鼠肾小球分离及肾小球系膜细胞(GMC)的培养方法,为进一步研究DN的发病机制奠定了方法学的基础。
Diabetic nephropathy (DN) is a common chronic microvascular complications of diabetes, causing great harm to humans, there is no effective prevention and treatment measures, so the study on the pathogenesis of DN has become a hot spot. This experiment established rat glomerular separation and culture of glomerular mesangial cells (GMC), which laid the foundation for further study on the pathogenesis of DN.