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目的探讨牙周干预治疗对牙周炎伴冠心病患者血清炎症因子及血脂水平的影响。方法选取2014年7月至2015年8月汝阳县中医院收治的牙周炎伴冠心病患者30例为试验组,给予内科治疗,并实施牙周治疗。同期患者30例为对照组,仅给予心内科治疗。于12周后,分别比较两组患者牙周指数及血脂水平。结果治疗后试验组患者牙石指数、菌斑指数、出血指数、附着丧失以及牙周袋探针深度均显著优于对照组(P<0.05)。试验组血清炎症因子水平低于对照组(P<0.05)。结论对于牙周炎合并冠心病患者,在进行心内科常规治疗的同时给予牙周干预治疗有助于改善牙周状况,降低炎症因子水平,进而提高临床治疗效果。
Objective To investigate the effect of periodontal intervention on serum inflammatory factors and serum lipids in patients with periodontitis and coronary heart disease. Methods Thirty patients with periodontitis and coronary heart disease admitted to Ruyang County Hospital of Traditional Chinese Medicine from July 2014 to August 2015 were selected as the experimental group for medical treatment and periodontal treatment. 30 cases of patients with the same period as the control group, giving only cardiology treatment. After 12 weeks, the periodontal index and blood lipid level were compared between the two groups. Results After treatment, the calculus index, plaque index, hemorrhage index, loss of attachment and probe depth of the periodontal pocket in the test group were significantly better than those in the control group (P <0.05). The level of serum inflammatory cytokines in the experimental group was lower than that in the control group (P <0.05). Conclusion For patients with periodontitis and coronary heart disease, periodontal interventional therapy while routine treatment of cardiology can improve the periodontal status, reduce the level of inflammatory cytokines, and then improve the clinical therapeutic effect.