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目的比较兰索拉唑与奥美拉唑治疗胃溃疡的临床疗效。方法选取2014年7月—2015年7月于九江市第六人民医院就诊的100例胃溃疡患者,按照随机分配的原则分为对照组和观察组,各50例。观察组给予兰索拉唑治疗,对照组患者给予奥美拉唑治疗。比较两组患者临床疗效,治疗后幽门螺杆菌(Hp)检测结果及不良反应发生情况。结果观察组患者总有效率高于对照组,Hp阳性率低于对照组,差异有统计学意义(P<0.05);两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论兰索拉唑治疗胃溃疡的愈合率高于奥美拉唑,配合甲硝唑与果胶铋胶囊效果更佳。
Objective To compare the clinical efficacy of lansoprazole and omeprazole in the treatment of gastric ulcer. Methods From July 2014 to July 2015, 100 patients with gastric ulcer who visited the Sixth People’s Hospital of Jiujiang City were divided into control group and observation group according to the principle of random distribution. The observation group was treated with lansoprazole and the control group with omeprazole. The clinical curative effect of two groups of patients was compared, the detection results of Helicobacter pylori (Hp) and the incidence of adverse reactions after treatment. Results The total effective rate of the observation group was higher than that of the control group, and the positive rate of Hp was lower than that of the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05) . Conclusions The healing rate of lansoprazole in the treatment of gastric ulcer is higher than that of omeprazole, with metronidazole and pectin bismuth capsules better.