论文部分内容阅读
目的:比较吸入沙美特罗/丙酸氟替卡松(SM/FP)治疗稳定期慢性阻塞性肺疾病(COPD)的疗效。方法:采用随机平行对照实验方法,将60例29~76岁肺功能Ⅱ~Ⅲ级的COPD患者随机分为治疗组(30例)和对照组(30例)。治疗组患者吸入SM/FP(50μg/250μg);对照组常规治疗。比较分析2组患者肺功能及住院次数变化。结果:经6个月的治疗,治疗组与对照组肺功能变化差异有统计学意义(P<0.05)。治疗组半年住院次数(3人次)少于对照组(7人次)。结论:长期联合吸入糖皮质激素和β2-受体激动剂治疗稳定期COPD的疗效优于非吸入治疗。
PURPOSE: To compare the efficacy of inhaled salmeterol / fluticasone propionate (SM / FP) in patients with stable chronic obstructive pulmonary disease (COPD). Methods: Sixty COPD patients aged from 29 to 76 years old with grade Ⅱ ~ Ⅲ pulmonary function were randomly divided into treatment group (30 cases) and control group (30 cases) by randomized controlled clinical trial. Patients in the treatment group inhaled SM / FP (50μg / 250μg); control group conventional treatment. The pulmonary function and the number of hospitalizations in two groups were compared and analyzed. Results: After 6 months of treatment, there were significant differences in lung function between treatment group and control group (P <0.05). The number of hospitalizations for half a year in the treatment group was less than that in the control group (3 visits) (7 visits). Conclusion: The long-term combined inhaled glucocorticoid and β2-receptor agonist in the treatment of stable COPD is superior to non-inhaled treatment.