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目的:研究家族性偏头痛对婴儿腹痛的影响及其相关性。方法:112例婴儿腹痛患儿为腹痛组,97例同期就诊非婴儿腹痛及头痛患儿为对照组,对所有患儿的一、二级及三级亲属进行问卷调查,然后对有偏头痛的亲属用统一的标准进行诊断,最后对两组患儿及其亲属的发病率进行对比分析。结果:20例(17.86%)婴儿腹痛患儿有家族性偏头痛,对照组6例(6.19%)患儿有家族性偏头痛,家族性患偏头痛的患儿比例在两组之间有显著差异(P<0.05);婴儿腹痛患儿的亲属诊断为偏头痛有85例,占本组调查总人数的16.93%,对照组患儿偏头痛亲属共有17例,占调查总人数的2.37%,两组患儿亲属患偏头痛的发病率有显著差异(P<0.05);患儿亲属患偏头痛种类的比较:腹痛组有家族性偏瘫型偏头痛和儿童腹型偏头痛,对照组没有;除散发性偏瘫型偏头痛的在两组的差异有统计学意义(P<0.05),其他种类的偏头痛没有显著差异。结论:有家族性偏头痛史的婴儿腹痛发生率高于正常人,婴儿腹痛与家族性偏头痛的发生率相关,与偏头痛的种类也可能有关。
PURPOSE: To study the effect of familial migraine on infant abdominal pain and its correlation. Methods: One hundred and twelve infants with abdominal pain were treated with abdominal pain, and 97 infants with non-infantile abdominal pain and headache during the same period were enrolled as control group. Questionnaires of primary, secondary and tertiary relatives of all infants were investigated. Relatives with a unified standard for diagnosis, the final comparison of the incidence of children and their relatives in two groups were analyzed. Results: In 20 infants with abdominal pain (17.86%), there were familial migraine children. Familial migraine was found in 6 (6.19%) children in the control group. The proportion of children with familial migraine headache was significantly higher in both groups (P <0.05). There were 85 relatives diagnosed as having migraine in infants with abdominal pain, accounting for 16.93% of the total number of migrants in this study. There were 17 migraine relatives in control group, accounting for 2.37% of the total. There were significant differences in the incidence of migraine between the two groups (P <0.05). The relatives of migrant children suffered from migraine: migraine with hemiplegia and migraine with abdominal pain were not found in the control group, There was a statistically significant difference between the two groups in spasmodic hemiplegia except for migraine (P <0.05). There was no significant difference in other types of migraine. CONCLUSIONS: The incidence of abdominal pain in infants with a history of familial migraine is higher than in normal subjects. Infant abdominal pain is associated with the incidence of familial migraine and may also be related to the type of migraine.