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目的:观察邓老益气化痰方联合西药治疗高血压病气虚痰湿证的效果。方法:将94例高血压病气虚痰湿证患者随机分为治疗组和对照组各47例。2组均采用苯磺酸氨氯地平片、阿托伐他汀钙片治疗,治疗组加服邓老益气化痰方,3月为1疗程,治疗1疗程。观察2组患者临床症状和血压的变化情况,评定中医证候积分,观察不良反应发生情况。结果:降压疗效:治疗组总有效率为80.4%,对照组总有效率为80.0%,2组比较,差异无统计学意义(P>0.05)。中医证候疗效:治疗组总有效率96.7%,对照组总有效率73.4%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组中医证候积分均较治疗前下降,差异均有统计学意义(P<0.01);2组中医证候积分比较,差异有统计学意义(P<0.01);2组治疗前后积分差值比较,差异均有统计学意义(P<0.05)。2组收缩压、舒张压与治疗前比较,差异均有统计学意义(P<0.05);2组收缩压差值和舒张压差值比较,差异均有统计学意义(P<0.05)。结论:邓老益气化痰方结合西药治疗气虚痰湿型高血压病患者,对血压具有明显的控制作用,能平稳降低血压,并改善患者的临床症状和体征。
Objective: To observe the effect of Dengli Yiqi Huatan Fang combined with western medicine in treating phlegm and dampness syndrome of hypertension with qi deficiency. Methods: 94 cases of hypertensive phlegm dampness syndrome patients were randomly divided into treatment group and control group of 47 cases. Both groups were treated with amlodipine besylate tablets and atorvastatin calcium tablets. The treatment group plus Deng Laoyi Qi and Phlegm prescription was given in March for 1 course of treatment for 1 course of treatment. The changes of clinical symptoms and blood pressure were observed in two groups of patients, the scores of TCM syndromes were evaluated, and the incidence of adverse reactions was observed. Results: The antihypertensive effect: The total effective rate was 80.4% in the treatment group and 80.0% in the control group. There was no significant difference between the two groups (P> 0.05). The efficacy of TCM syndromes: The total effective rate was 96.7% in the treatment group and 73.4% in the control group. There was significant difference between the two groups (P <0.05). After treatment, the scores of TCM syndromes in both groups were significantly lower than those before treatment (P <0.01), and the difference was statistically significant (P <0.01) Differences between the points, the differences were statistically significant (P <0.05). The systolic blood pressure and diastolic blood pressure of the two groups were significantly different from those before treatment (P <0.05). There was significant difference between the two groups in the systolic blood pressure and diastolic blood pressure (P <0.05). Conclusion: The treatment of Qi-deficiency and phlegm-dampness-induced hypertension in patients with Qi-deficiency and phlegm-dampness syndrome with Denglian Yiqi Huatan Fang combined with western medicine has significant control on blood pressure, which can reduce blood pressure smoothly and improve clinical symptoms and signs of patients.