喉癌发病率占头颈部肿瘤35%。黑龙江省的喉癌发病率居全国首位。大量研究表明ｎｍ23Ｈ1基因在抑制喉癌淋巴结转移方面起作用。ｎｍ23Ｈ1是一种肿瘤转移抑制基因。ｎｍ23基因的表达降低或等位基因缺失及基因突变与肿瘤的高转移潜力有关[1]。本研究应用多聚酶链反应—单链构象银 The incidence of laryngeal cancer accounts for 35% of head and neck cancer. The incidence of laryngeal cancer in Heilongjiang Province ranks first in the country. A large number of studies have shown that nm23H1 gene plays a role in inhibiting lymph node metastasis of laryngeal cancer. nm23H1 is a tumor metastasis suppressor gene. Decreased expression of nm23 gene or allelic loss and gene mutation and tumor metastasis potential [1]. In this study, polymerase chain reaction - single strand conformation of silver