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目的探究2型糖尿病无症状心肌缺血发作与心率变异性的临床相关性。方法选择2014年1月至2016年1月2型糖尿病患者106例,均接受运动负荷心肌灌注显像检查,且1周内采用动态心电图实时监测其心脏情况,其中53例出现无症状心肌缺血现象2型糖尿病患者为实验组,另外53例未出现无症状心肌缺血现象2型糖尿病患者为对照组,将两组患者动态心电图的各种参数进行分析比较。结果 RR间期标准差均值(SDNNI)、全部窦性心搏RR间期(SDNN)、RR间期平均值标准差(SDANN)、相邻RR间期差值的均方根(RMSSD)、相邻NN之差>50 ms的个数占总窦性心搏个数的百分比(PNN50)以及平均心率都是心率变异性的重要参数,本研究结果显示,实验组各项参数(除平均心率外)均低于对照组,差异有统计学意义(P<0.05)。结论患者心率变异性各项参数降低,极大地增加了患者无症状心肌缺血发作的可能性。因此对于2型糖尿病患者可以通过心率变异性各项参数的分析来筛选出患者是否易发生无症状心肌缺血现象。
Objective To investigate the clinical correlation between asymptomatic myocardial ischemia and heart rate variability in type 2 diabetic patients. Methods From January 2014 to January 2016, 106 patients with type 2 diabetes mellitus received exercise-load myocardial perfusion imaging, and their electrocardiogram was used to monitor the heart condition in real time in one week. Of them, 53 patients had asymptomatic myocardial ischemia Phenomenon Type 2 diabetes patients as experimental group, another 53 cases of type 2 diabetes mellitus without asymptomatic myocardial ischemia as control group, the two groups of patients were analyzed and compared various parameters of ambulatory electrocardiogram. Results The mean standard deviation of RR interval (SDNNI), total sinus RR interval (SDNN), standard deviation of RR interval (SDANN), root mean square (RMSSD) of adjacent RR intervals, The difference between the number of total sinus beats (PNN50) and average heart rate (> 50 ms) are important parameters of heart rate variability. The results of this study showed that the parameters of the experimental group (except the average heart rate) Control group, the difference was statistically significant (P <0.05). Conclusion The parameters of heart rate variability decreased, which greatly increased the possibility of asymptomatic myocardial ischemia. Therefore, for patients with type 2 diabetes heart rate variability through the analysis of the parameters to screen out whether the patient prone to asymptomatic myocardial ischemia phenomenon.