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目的:观察四君子汤联合微量喂养的方法治疗新生儿窒息后喂养不耐受的临床疗效及其对血液胃动素和一氧化氮的影响。方法:将52例窒息后发生喂养不耐受的新生儿随机分为两组各26例,对照组采用全胃肠外营养,治疗组采用微量喂养联合应用四君子汤进行治疗。对两组患儿的临床疗效以及治疗前后血液胃动素和一氧化氮水平进行动态监测和比较。结果:治疗组患儿在症状的消失、体质量的恢复以及达到有效的胃肠道营养摄入的时间上均优于对照组,同时其血液胃动素和一氧化氮水平的恢复更为迅速。结论:采用四君子汤联合微量喂养的方法可以对胃肠道功能以及胃肠道激素分泌水平起到有效的调理作用,从而促进临床症状的改善。
Objective: To observe the clinical efficacy of Sijunzi Decoction combined with micronutrient feeding in the treatment of neonatal asphyxia feeding intolerance and its effect on motilin and nitric oxide in blood. Methods: Fifty-two neonates with intolerance after asphyxiation were randomly divided into two groups of 26 cases. The control group received total parenteral nutrition. The treatment group was treated with micro-feeding combined with Sijunzi Decoction. The clinical efficacy of both groups of children and before and after treatment of blood motilin and nitric oxide levels were dynamically monitored and compared. Results: The children in the treatment group were better than the control group in symptom disappearance, body weight recovery and effective gastrointestinal nutrition intake, and their blood motilin and nitric oxide levels recovered more rapidly . Conclusion: The combination of Sijunzi Decoction and micro-feeding can effectively regulate the function of gastrointestinal tract and the secretion of gastrointestinal tract hormones, thus improving the clinical symptoms.