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目的:优选护肝拔毒浸膏乙醇提取工艺条件。方法:采用正交试验设计,以苦参碱和氧化苦参碱的含量以及浸出物得率为考察指标,优选护肝拔毒浸膏醇提工艺条件。结果:护肝拔毒浸膏的最佳醇提工艺条件为用饮片总量15倍量60%乙醇分3次回流提取,每次2 h。结论:此工艺稳定可行。
Objective: To optimize the extraction conditions of ethanol extract from liver extract. Methods: Orthogonal design was used to investigate the content of matrine and oxymatrine and the yield of extract. Results: The optimal extraction conditions for the extraction of liver extract poisoning extract with 15 times the total amount of 60% ethanol was refluxed three times, each 2 h. Conclusion: This process is stable and feasible.