研究地奥心血康对高脂血症大鼠血脂及脂蛋白的影响。用高脂饲料喂服雄性ｗｉｓｔａｒ大鼠，复制高脂血症大鼠模型。动物分５组：１、正常对照组：给予基础饲料＋生理盐水。２、高脂模型组：高脂饲料＋生理盐水。３－４、地奥心血康０１０、０２０ｇ／ｋｇ组：高脂饲料＋地奥心血康；５、阳性药肌醇烟酸酯组：高脂饲料＋肌醇烟酸酯（０１ｇ／ｋｇ），连续灌胃给药１０ｄ后采血，测定血清甘油三脂（ＴＧ），总胆固醇（ＴＣ），高密度脂蛋白（ＨＤＬ－Ｃ），计算低密度脂蛋白（ＬＤＬ－Ｃ）。地奥心血康０２０、０１０ｇ／ｋｇ均能明显降低高脂血症大鼠ＴＣ、ＴＧ、ＬＤＬ－Ｃ（Ｐ＜００５Ｐ＜００１（与高脂模型组比），分别使ＴＣ降低３０％、１９％；ＴＣ降低４５％、２０％；使ＬＤＬ－Ｃ降低５７％、３１％；０２０ｇ／ｋｇ也能升高ＨＤＬ－Ｃ，为１２％。地奥心血康能降低高脂血症大鼠ＴＣ、ＴＧ、ＬＤＬ－Ｃ水平而升高ＨＤＬ－Ｃ水平 To study the effect of Aoxixuekang on blood lipids and lipoproteins in hyperlipidemic rats. Male Wistar rats were fed with high-fat diet and hyperlipidemia rats were duplicated. Animals divided into 5 groups: 1, normal control group: given basal diet + saline. 2, high-fat model group: high fat diet + saline. 3-4, DiaoXinKangKang 0  10,0  20g / kg group: high-fat feed + Dioxintangkang; 5, the positive drug inositol nicotinate group: high fat diet + inositol nicotinate (0 1g / kg) Blood was collected 10 days after continuous intragastric administration, and serum triglyceride (TG), total cholesterol (TC), high density lipoprotein (HDL-C) and low density lipoprotein (LDL-C) were calculated. Dioshen Xuexinkang 020,010g / kg can significantly reduce hyperlipidemic rats TC, TG, LDL-C (P <0  05P <0  01 (compared with the high-fat model group), respectively, so that TC decreased 30%, 19%; TC reduced by 45%, 20%; LDL-C decreased by 57%, 31%; 0  20g / kg also increased HDL-C, Rat TC, TG, LDL-C levels and increased HDL-C levels