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过去抑制产褥期泌乳采取对乳房的机械压迫、限制液体摄入、给予雌激素或雌激素与雄激素合用。由于产褥期泌乳与垂体催乳素(PRL)的分泌有关,故有用降低 PRL 作用的药物来抑制产后泌乳。所有这些药物皆为具多巴胺促进作用的麦角衍生物如溴亭、麦角乙素(Lisuride),或5羟色胺拮抗剂(麦角苄酯 Metergoline)。用这些药物作为抑制泌乳皆需长时间给药,给予多个剂量(每日3次,共7～15天)此外这些药物还会造成一些与激活中枢多巴胺受体有关的副作用。本文探索一
In the past to suppress the puerperal lactation to take mechanical compression of the breast, limiting fluid intake, given estrogen or estrogen and androgen combined. Because of puerperium lactation and pituitary prolactin (PRL) secretion, it is used to reduce the role of PRL drugs to inhibit postpartum lactation. All of these drugs are ergot derivatives such as bromine booths, lisuride, or serotonin antagonists (Metergoline) with dopamine potentiation. Multiple doses of these drugs are required for prolonged administration of lactation (three times a day for seven to fifteen days). In addition, these drugs also cause some side-effects associated with activation of central dopamine receptors. This article explores one