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目的 探讨苯对大鼠总抗氧化能力 (Totalantioxidantcapacity ,TAC)的影响。方法 应用化学比色法检测大鼠血清中TAC含量 ,同时利用直接计数法计数大鼠全血白细胞 (WBC)总数。结果 苯使染毒大鼠血清TAC含量明显降低 ,与WBC计数结果一致。结论 TAC水平的改变可能是苯毒性作用的重要方面。
Objective To investigate the effect of benzene on total antioxidant capacity (TAC) in rats. Methods TAC levels in serum of rats were detected by chemical colorimetry, and the total count of white blood cells (WBC) in rats was measured by direct counting method. Results Compared with WBC, the TAC content of benzene in rats exposed to benzene decreased significantly. Conclusions Changes in TAC levels may be an important aspect of the toxic effects of benzene.